HC115868_cDNA克隆_基因库_赢润生物-中国基因研究资源库
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人 CYP2E1 (NM_000773) cDNA 克隆产品信息

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货号 种属 载体 描述 价格 周期
HC115868 Human cDNA pYr-CMV Homo sapiens cytochrome P450, family 2, subfamily E, polypeptide 1 (CYP2E1), mRNA. NM_000773
1-2个工作日发货   已测序验证  
1500
1200
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基本信息

基因名称: CYP2E1
基因别名: CPE1; CYP2E; P450-J; P450C2E
NCBI序列号: NM_000773
基因描述: Homo sapiens cytochrome P450, family 2, subfamily E, polypeptide 1 (CYP2E1), mRNA. NM_000773
基因种属: Human

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基因简介

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.

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