HC118828_cDNA克隆_基因库_赢润生物-中国基因研究资源库
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人 GAD2 (BC126327) cDNA 克隆产品信息

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货号 种属 载体 描述 价格 周期
HC118828 Human cDNA pDONR223 Homo sapiens glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) (GAD2), transcript variant 1, mRNA NM_000818 BC126327
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基本信息

基因名称: GAD2
基因别名: GAD65; MGC161605; MGC161607
NCBI序列号: BC126327
基因描述: Homo sapiens glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) (GAD2), transcript variant 1, mRNA NM_000818 BC126327
基因种属: Human

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载体信息

基因简介

This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.

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