HO003335_ORF克隆_基因库_赢润生物-中国最大的基因研究资源库
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人 UBA7 (NM_003335) ORF克隆产品信息

订购信息

货号 种属 载体 描述 价格 周期
HO003335 Human ORF pYr-CMV-Kan (C端带flag标签)Homo sapiens ubiquitin like modifier activating enzyme 7 (UBA7),mRNA NM_003335 4500
4000
1-2 周

基本信息

基因名称: UBA7
NCBI序列号: NM_003335
基因描述: (C端带flag标签)Homo sapiens ubiquitin like modifier activating enzyme 7 (UBA7),mRNA NM_003335
基因种属: Human

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基因简介

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein.

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