LV002585_过表达慢病毒_赢润生物-中国最大的基因研究资源库
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人 PBX1 (NM_002585) 过表达慢病毒产品信息

订购信息

货号 种属 载体 描述 荧光 价格 周期
LV002585 Human 腺病毒 Homo sapiens pre-B-cell leukemia homeobox 1 (PBX1), transcript variant 1, mRNA NM_002585 无荧光 8500
8000
6-7 周

基本信息

基因名称: PBX1
NCBI序列号: NM_002585
基因描述: Homo sapiens pre-B-cell leukemia homeobox 1 (PBX1), transcript variant 1, mRNA NM_002585
基因种属: Human
荧光标记: 无荧光
慢病毒滴度: 108 TU/ml

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基因简介

This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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