LV011577_过表达慢病毒_赢润生物-中国最大的基因研究资源库
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小鼠 TGFB1 (NM_011577) 过表达慢病毒产品信息

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货号 种属 载体 描述 荧光 价格 周期
LV011577 Mouse 腺病毒 Mus musculus transforming growth factor, beta 1 (Tgfb1), mRNA NM_011577 无荧光 8000 3-4 周

基本信息

基因名称: TGFB1
NCBI序列号: NM_011577
基因描述: Mus musculus transforming growth factor, beta 1 (Tgfb1), mRNA NM_011577
基因种属: Mouse
荧光标记: 无荧光
慢病毒滴度: 108 TU/ml

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基因简介

This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.

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