rAd024630_过表达腺病毒库_赢润生物-中国基因研究资源库
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人 RUNX2 (NM_001024630) 过表达腺病毒产品信息

订购信息

货号 种属 载体 描述 荧光 价格 周期
rAd024630 Human 腺病毒 Homo sapiens runt-related transcription factor 2 (RUNX2),transcript variant 1, mRNA NM_001024630 带绿色荧光 9000
8500
4-5 周

基本信息

基因名称: RUNX2
NCBI序列号: NM_001024630
基因描述: Homo sapiens runt-related transcription factor 2 (RUNX2),transcript variant 1, mRNA NM_001024630
基因种属: Human
荧光标记: 带绿色荧光
腺病毒滴度: 109~1010pfu/ml

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基因简介

This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing.

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