PRO002253_启动子库_赢润生物-中国最大的基因研究资源库
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KDR 启动子产品信息

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货号 种属 载体 描述 价格 周期
PRO002253 Human pMD19-T Simple Vector (KDR启动子,约1.3K)Homo sapiens kinase insert domain receptor (a type III receptor tyrosine kinase)(KDR,CD309,FLK1,VEGFR,VEGFR2), mRNA NM_002253
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Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.

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