PR10242_启动子库_赢润生物-中国最大的基因研究资源库
您好,欢迎光临赢润生物技术商城
请登录    |     免费注册     帮助中心

客服热线:0731—84317068

QQ咨询:12695920

订货邮箱:service@yrgene.com

当前位置: 首页 > 启动子库

启动子产品信息

订购信息

货号 种属 载体 描述 价格 周期
PR10242 Mouse pDRIVE5-SEAP 3500 3-4 周

产品参数

Gene Promoter: Interferon Beta
Specificity: Hematopoietic cells
Backbone: pDRIVE, pDRIVE5-SEAP, pGL3-basic, pUC57, pcDNA3.1-EGFP, ect.

产品说明书

pDRIVE-INF-β(mouse) Map 产品说明书(点击下载)

产品说明

Description:
Expression of the interferon-beta (IFN-β) gene is induced by a variety of agents, including viruses and double-stranded RNA (dsRNA), and is also strongly repressed in uninduced cells, a requirement imposed by the cytotoxic properties of IFN-β. The functional IFN-β promoter resides within a 170 bp fragment located 5’ of the coding sequence [1]. This region contains four binding sites for transcription factors such as NF-κB and IRF-1 that act as activators, as well as putative negative regulatory domains. Fusion of the IFN-β promoter region to the luciferase gene was shown to render the expression of the reporter gene inducible by dsRNA [2].


1. Dirks W. et al., 1989. Isolation and functional characterization of the murine interferon-beta 1 promoter. J Interferon Res. 9(1):125-33.
2. King P& Goodbourn S. 1994. The betainterferon promoter responds to priming through multiple independent regulatory elements. J Biol Chem. 269(48):30609-15.

立即购买 加入购物车

Copyright ©2014 长沙赢润生物技术有限公司版权所有 湘ICP备15013987号-2

技术支持