PR10230_启动子库_赢润生物-中国最大的基因研究资源库
您好,欢迎光临赢润生物技术商城
请登录    |     免费注册     帮助中心

客服热线:0731—84317068

QQ咨询:12695920

订货邮箱:service@yrgene.com

当前位置: 首页 > 启动子库

启动子产品信息

订购信息

货号 种属 载体 描述 价格 周期
PR10230 Rattus pDrive 3500 3-4 周

产品参数

Gene Promoter: Glial Fibrillary Acidic Protein
Specificity: Astrocytes
Backbone: pDRIVE, pDRIVE5-SEAP, pGL3-basic, pcDNA3.1-EGFP, ect.

产品说明书

pDRIVE-GFAP(human) Map 产品说明书(点击下载)

pDRIVE-GFAP(human) Sequence 产品说明书(点击下载)

pDRIVE-GFAP(mouse) Map 产品说明书(点击下载)

pDRIVE-GFAP(mouse) Sequence 产品说明书(点击下载)

pDRIVE-GFAP(rat) Map 产品说明书(点击下载)

产品说明

Description:
The glial fibrillary acidic protein (GFAP) is an intermediate filament protein found almost exclusively in astrocytes. It is expressed throughout postnatal life and is upregulated in response to almost any damage to the central nervous system, including Parkinson's disease. The promoter of the GFAP gene was shown to direct astrocyte-specific transcription in vitro, in vivo [1], and in transgenic mice [2]. Expression of a transgene under the control of the GFAP promoter is regulated in a similar fashion as the endogenous GFAP gene [3].


1. Vandier et al. 2000. Inhibition of glioma cells in vitro and in vivo using a recombinant adenoviral vector containing an astrocyte-specific promoter. Cancer Gene Ther 7:1120-6.
2. Brenner et al. 1994. GFAP promoter directs astrocyte-specific expression in transgenic mice. Neurosci. 14:1030-7.
3. Jakobsson J. et al., 2004. Lesion-dependent regulation of transgene expression in the rat brain using a human glial fibrillary acidic protein-lentiviral vector. Eur J Neurosci. 19(3):761-5.

立即购买 加入购物车

Copyright ©2014 长沙赢润生物技术有限公司版权所有 湘ICP备15013987号-2

技术支持