PR10166_启动子库_赢润生物-中国基因研究资源库
您好,欢迎光临赢润生物技术商城
请登录    |     免费注册     帮助中心

客服热线:0731—84317068

QQ咨询:12695920

订货邮箱:service@yrgene.com

当前位置: 首页 > 启动子库

启动子产品信息

订购信息

货号 种属 载体 描述 价格 周期
PR10166 Human pUC57 2500 2-3 周

产品参数

Gene Promoter: Alb: Albumin
Specificity: Liver
Backbone: pDRIVE, pDRIVE5-SEAP, pGL3-basic, pUC57, pcDNA3.1-EGFP, ect.

产品说明书

pDRIVE-SV40 / hAlb(human) Map 产品说明书(点击下载)

pDRIVE-SV40 / hAlb(human) Sequence 产品说明书(点击下载)

pDRIVE5-SEAP-SV40 / hAlb(human) Map 产品说明书(点击下载)

产品说明

Description:
The albumin gene is transcribed at very high levels in fetal liver and, unlike the adjacent AFP gene, remains active after birth. A small segment of the bovine albumin 5’flanking region, from -170 to +20, is sufficient for promoter activity and specificity [1]. This segment contains the CCAAT box, TATA box and the binding site of HNF1, a liver specific transcription factor. The albumin promoter is a liver-specific promoter. It can drive the expression of a transgene, such as HSV-tk, specifically in hepatocellular carcinoma cells eliminating the risk of systemic toxicity of GCV [2].


1. Power SC. et al. 1994. Isolation and functional analysis of the promoter of the bovine serum albumin gene. Biochem Biophys Res Com 203(3):1447-1456.
2. Kuriyama S. et al. 1997. Tissue-specific expression of HSV-tk gene can induce efficient antitumor effect and protective immunity to wild-type hepatocellular carcinoma. Int J Cancer. 71(3):470-5.

立即购买 加入购物车

Copyright ©2014 长沙赢润生物技术有限公司版权所有 湘ICP备15013987号-2

技术支持