PR10041_启动子库_赢润生物-中国基因研究资源库
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货号 种属 载体 描述 价格 周期
PR10041 Human pGL3-basic 3000 3-4 周

产品参数

Gene Promoter: Eukaryotic Initiation Factor 4A1
Specificity: Ubiquitous
Backbone: pDRIVE, pDRIVE5-SEAP, pGL3-basic, pUC57, pcDNA3.1-EGFP, ect.

产品说明书

pDRIVE-heIF4A1(human) Sequence 产品说明书(点击下载)

pDRIVE-heIF4A1(human&mouse) Map 产品说明书(点击下载)

pDRIVE-heIF4A1(mouse) Sequence 产品说明书(点击下载)

pDRIVE5-SEAP-heIF4A1(mouse) Map 产品说明书(点击下载)

pDRIVE5-SEAP-heIF4A1(mouse) Sequence 产品说明书(点击下载)

产品说明

Description:
The eIF-4A1 gene encoding eukaryotic initiation factor 4A is ubiquitously expressed in eukaryotic cells. The minimal promoter of the eIF-4A1 gene consists of approximately 300 bp, 80% of which are identical with those in mouse eIF-4A1 promoter. The minimal promoter contains TATA and CAAT motifs and consensus sequences binding to SP1 and AP2 [1]. The eIF-4A1 promoter is a versatile promoter giving high-levels of expression. In some cell lines, such as macrophages, levels of expression are higher than that obtained with the CMV promoter [2].


1. Kukimoto I. et al. 1997. Characterization of the cloned promoter of the human initiation factor 4AI gene. Biochem Biophys Res Commun 233(3):844-7.
2. Quinn CM. et al. 1999. The human eukaryotic initiation factor 4AI gene (EIF4A1) contains multiple regulatory elements that direct high-level reporter gene expression in mammalian cell lines. Genomics 62(3):468-76.

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