rAd004360_过表达腺病毒库_赢润生物-中国基因研究资源库
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人 CDH1 (NM_004360) 过表达腺病毒产品信息

订购信息

货号 种属 载体 描述 荧光 价格 周期
rAd004360 Human 腺病毒 Homo sapiens cadherin 1 (CDH1,CD324,CDHE,ECAD,LCAM), transcript variant 1, mRNA NM_004360 带绿色荧光 10500 6-7 周

基本信息

基因名称: CDH1
NCBI序列号: NM_004360
基因描述: Homo sapiens cadherin 1 (CDH1,CD324,CDHE,ECAD,LCAM), transcript variant 1, mRNA NM_004360
基因种属: Human
荧光标记: 带绿色荧光
腺病毒滴度: 109~1010pfu/ml

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基因简介

This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16.

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